Journal of Antimicrobial Chemotherapy 2008, 62(1):5-34
Guidelines for the Management of Hospital-Acquired Pneumonia in the UK: Report of the Working Party on Hospital-Acquired Pneumonia of the British Society for Antimicrobial Chemotherapy
R. G. Masterton1, A. Galloway2, G. French3, M. Street4, J. Armstrong5, E. Brown6, J. Cleverley7, P. Dilworth8, C. Fry9, A. D. Gascoigne10, Alan Knox11, Dilip Nathwani12, Robert Spencer13, and Mark Wilcox14
1Department of Microbiology, Crosshouse Hospital, Kilmarnock, UK, 2Department of Microbiology, Royal Victoria Infirmary, Queen Victoria Road, Newcastle-upon-Tyne, UK, 3Department of Infection, Guy's and St Thomas's NHS Foundation Trust and King's College, St Thomas' Hospital, London, UK, 4Department of Intensive Care, Royal Sussex County Hospital, Brighton, UK, 5Department of Public Health, North Durham Strategic Health Authority, Earls House, Durham, UK, 6Department of Microbiology, Frenchay Hospital, Bristol, UK, 7Department of Radiology, Royal Free Hospital, London, UK, 8Department of Thoracic Medicine, Royal Free Hospital, London, UK, 9Department of Health, London, UK, 10Royal Victoria Infirmary, Queen Victoria Road, Newcastle-upon-Tyne, UK, 11Respiratory Medicine Unit, City Hospital, Nottingham, UK, 12Infection Unit, Ninewells Hospital and Medical School, Dundee, UK, 13Health Protection Agency, Bristol Royal Infirmary, Marlborough St, Bristol, UK, 14University of Leeds, Leeds, UK
|These evidence-based guidelines have been produced after a systematic literature review of a range of issues involving prevention, diagnosis and treatment of hospital-acquired pneumonia (HAP). Prevention is structured into sections addressing general issues, equipment, patient procedures and the environment, whereas in treatment, the structure addresses the use of antimicrobials in prevention and treatment, adjunctive therapies and the application of clinical protocols. The sections dealing with diagnosis are presented against the clinical, radiological and microbiological diagnosis of HAP. Recommendations are also made upon the role of invasive sampling and quantitative microbiology of respiratory secretions in directing antibiotic therapy in HAP/ventilator-associated pneumonia.